Michael K Pasque

Title: Michael K Pasque: Innovator in Cardiac Imaging Technologies

Introduction

Michael K Pasque, an accomplished inventor based in St. Louis, MO, has made significant contributions to the field of cardiac imaging. With 13 patents to his name, Pasque has developed advanced methodologies that enhance the understanding and measurement of cardiac function.

Latest Patents

Among Pasque's latest innovations are two notable patents focusing on cardiac strain measurement and analysis. The first patent introduces systems and methods for measuring cardiac strain through a novel approach for rapid computation of three-dimensional displacement and Lagrange strain using phase data from magnetic resonance images (MRI) of the myocardium. This method includes semi-automated segmentation of the heart, three-dimensional phase unwrapping, and a unique radial point interpolation method (RPIM), which is a meshfree numerical analysis technique that incorporates radial basis and polynomial functions to calculate Lagrange strain.

The second patent focuses on quantitatively mapping myocardial contractile function through a magnetic resonance-based multiparametric strain analysis. This process determines strain at various locations in the heart by acquiring a series of MR images using a tagging pulse sequence that creates a grid pattern in reconstructed images. The process calculates circumferential strain, longitudinal strain, and minimum principal strain angle, normalizing these values against a stored reference model to form a composite multiparametric strain index reflective of myocardial contractile function, effectively enhancing the anatomical representation of the heart's performance.

Career Highlights

Throughout his career, Michael K Pasque has worked with reputable organizations that have positioned him as an innovative leader in his field. Notably, he has contributed his expertise to Electric Boat Corporation, where he applied his engineering skills and inventive mindset to develop advanced technologies.

Collaborations

Pasque has collaborated with prominent professionals in his field, including Carl O Larson, Jr and James S Smith. These collaborations have facilitated the exchange of ideas and expertise, further enriching the innovative developments in cardiac imaging technology.

Conclusion

With an impressive portfolio of patents and groundbreaking work in cardiac imaging, Michael K Pasque exemplifies the spirit of innovation in medical technology. His contributions not only advance the field of cardiac research but also pave the way for improved patient care through better diagnostic and monitoring techniques.