Michael J Robarge

Title: Innovations by Michael J Robarge: Pioneering Breast Cancer Chemoprevention

Introduction

Michael J Robarge, an accomplished inventor based in Columbus, OH, has made significant contributions to the field of biomedical research. With a commendable portfolio of two patents, Robarge is particularly noted for his work on C-glycoside analogues that hold promise in breast cancer chemoprevention. His innovative approaches aim to improve the effectiveness and stability of drug compounds linked to the treatment of breast cancer.

Latest Patents

Robarge’s latest patents revolve around the development of breast cancer chemopreventive arylamide analogues of retinoic acid. Specifically, his work focuses on C-glycoside analogues of N-(4-hydroxyphenyl)retinamide-O-glucuronide and N-glycoside analogues of retinoyl .beta.-glucuronide. These compounds have been designed to resist enzymatic hydrolysis mediated by .beta.-glucuronidase, as well as acid-catalyzed hydrolysis, ensuring enhanced therapeutic efficacy. Among the specific drugs outlined in his patents, the compounds include 4-(retinamido)phenyl-C-glucuronide, 4-(retinamido)phenyl-C-glucoside, and 1-(D-glucopyranosyluronosly) retinamide, each showcasing potential benefits in combating breast cancer.

Career Highlights

Michael J Robarge works with the Ohio State Research Foundation, a prominent organization dedicated to advancing research and innovation. His role in the foundation underscores his commitment to translating scientific research into viable medical solutions. With a background that supports his expertise in biomedical chemistry, Robarge continues to push the boundaries of cancer research through his innovative work.

Collaborations

Throughout his career, Robarge has collaborated with prominent figures in the field, including his coworker Robert W Curley, Jr. These collaborative efforts highlight the importance of teamwork in scientific advancements, as they combine diverse expertise to address complex challenges in biomedical research.

Conclusion

Michael J Robarge's innovative contributions to the field of breast cancer chemoprevention reflect a dedication to improving health outcomes through scientific research. With two patents emphasizing novel drug formulations, Robarge is paving the way for future advancements in cancer treatment, illustrating the critical role of inventors in the medical field. His ongoing work at the Ohio State Research Foundation promises further impact in the realm of biotechnology and pharmacology.