Highland Mills, NY, United States of America

Michael J Pastel


Average Co-Inventor Count = 3.0

ph-index = 2

Forward Citations = 116(Granted Patents)


Company Filing History:


Years Active: 1993-1995

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2 patents (USPTO):Explore Patents

Title: The Innovative Mind of Michael J. Pastel: A Pioneer in Photodynamic Therapy

Introduction: Michael J. Pastel, hailing from Highland Mills, NY, is a notable inventor whose contributions to the field of photodynamic therapy have established him as a significant figure in medical innovations. With a total of two patents to his name, Pastel's work focuses on the development of stable porfimer sodium compositions, which have promising applications in cancer treatment.

Latest Patents: Among his most recent patents, Pastel has developed a "Stable porfimer sodium compositions and methods for their manufacture." This innovative composition is characterized by a storage-stable porfimer sodium (polyhematoporphyrin ether/ester) formulation, which is particularly useful in photodynamic therapy for cancer and other medical conditions. The composition consists of less than 10% ester-linked porphyrin oligomers, a critical aspect that enhances its effectiveness. Additionally, Pastel's improved processes for preparing these compositions involve treating acetylated hematoporphyrin with alkali at controlled temperatures and durations to minimize the ester-linked porphyrin oligomers.

Career Highlights: Michael J. Pastel's career is marked by his significant contributions to American Cyanamid Company, where he has played an integral role in advancing research on photodynamic therapy. His innovative approach to developing stable compositions for medical applications has not only benefited the field of oncology but has also paved the way for future research in photophysical agents.

Collaborations: Throughout his professional journey, Pastel has collaborated with notable colleagues, including Steven L. Clauss and Rainer K. Zawadzki. This collaborative environment has enabled the exchange of ideas and expertise, which is essential for driving innovation in complex scientific fields such as photodynamic therapy.

Conclusion: Michael J. Pastel stands out as an inventor whose work in stable porfimer sodium compositions significantly impacts the realm of cancer treatment and photodynamic therapy. His dedication to advancing medical technologies underscores the importance of innovation in improving healthcare outcomes. As research in this area continues to evolve, Pastel's contributions will undoubtedly inspire future developments and innovations in the field.

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