Lexington, MA, United States of America

Michael J Briskin

USPTO Granted Patents = 8 

Average Co-Inventor Count = 1.8

ph-index = 3

Forward Citations = 47(Granted Patents)


Company Filing History:


Years Active: 2001-2012

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8 patents (USPTO):Explore Patents

Title: Michael J Briskin: A Pioneer in Mucosal Vascular Addressins

Introduction

Michael J Briskin, an accomplished inventor based in Lexington, MA, has contributed significantly to the field of biomedical research with his innovative inventions. With a total of 8 patents to his name, Briskin stands out as a key figure in the development of therapeutic antibodies and fusion proteins targeting mucosal vascular addressins.

Latest Patents

Among his latest inventions, two noteworthy patents focus on mucosal vascular addressins and their applications. The first patent describes isolated antibodies and antigen-binding fragments that specifically bind to naturally occurring human MAdCAM (Mucosal Addressin Cell Adhesion Molecule). These antibodies not only inhibit the binding of human MAdCAM to the human integrin α4β7 but also block the adhesion of RPMI 8866 cells to MAdCAM-expressing cells. The second patent presents fusion proteins that encompass a naturally occurring primate MAdCAM, which shows significant amino acid similarity to established sequences, thus facilitating its binding capability to α4β7 integrin.

Career Highlights

Briskin has made an indelible mark in the biomedical sector through his tenure at Millennium Pharmaceuticals Limited. His focused research and innovative approach have garnered attention, establishing him as an expert in the realm of mucosal immunology and antibody development.

Collaborations

Throughout his career, Michael J Briskin has collaborated with several distinguished colleagues, including Kristine E Murphy and Alyson M Wilbanks. These partnerships have played a crucial role in enhancing the scope and impact of his research endeavors, leading to significant advancements in the field.

Conclusion

In conclusion, Michael J Briskin continues to be a driving force in the field of biomedical innovation. His patents on mucosal vascular addressins not only highlight his expertise but also pave the way for future therapeutic developments that could improve patient outcomes. The work of Briskin and his colleagues remains vital in transforming scientific research into practical applications that benefit society.

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