Michael H Tomasson

Title: Innovations in Multiple Myeloma Genomics by Michael H Tomasson

Introduction

Michael H Tomasson is a notable inventor based in Coralville, IA (US). He has made significant contributions to the field of genomics, particularly in the study of multiple myeloma. His work focuses on developing innovative methods for identifying genomic variants that can lead to personalized treatment plans for patients.

Latest Patents

Tomasson holds a patent for an invention titled "Automated exposition of known and novel multiple myeloma genomic variants using a single sequencing platform." This patent describes a sequencing capture array designed to identify mutations in multiple myeloma. The invention includes targeted next-generation sequencing methods for detecting single nucleotide variants (SNV), copy number variations (CNV), and translocation mutations in tumor cells. The capture array can analyze fewer than 500 genes implicated in multiple myeloma, facilitating the creation of personalized treatment plans for patients. The analytical methods presented allow for tumor mutations to be elucidated with coverage at a sequencing depth of no more than 500×, or as low as 100×, with optimal efficiency achieved at a sequencing depth of about 300×.

Career Highlights

Tomasson is affiliated with Washington University, where he continues to advance research in the field of genomics. His work has garnered attention for its potential to improve treatment outcomes for patients suffering from multiple myeloma.

Collaborations

Throughout his career, Tomasson has collaborated with esteemed colleagues, including Robert Fulton and Daniel Auclair. These collaborations have contributed to the advancement of research and innovation in the field.

Conclusion

Michael H Tomasson is a pioneering inventor whose work in multiple myeloma genomics is paving the way for more effective and personalized treatment options. His contributions to the field are invaluable and continue to impact patient care positively.