Company Filing History:
1 out of 2 
1 out of 832,966 Years Active: 2021-2023
Title: Michael Gregory Branden: Innovator in Glycosylation Methods
Introduction
Michael Gregory Branden is an accomplished inventor based in Lawrence, KS (US). He has made significant contributions to the field of glycosylation, particularly in the development of methods for producing glycosylated proteins. With a total of 2 patents, his work has implications for various applications, including biosensor technology.
Latest Patents
Branden's latest patents focus on innovative in vitro glycosylation methods. These methods provide rational approaches for producing glycosylated proteins and their subsequent uses. Specifically, the invention involves glycosylating a starting protein that has an amino sidechain with a nucleophilic moiety. This is achieved by reacting the protein with a carbohydrate that has an oxazoline moiety on its reducing end. The result is a glycosylated protein that retains the structure and function of the original protein. Target proteins for this method include oxidase, oxidoreductase, and dehydrogenase enzymes. The glycosylated proteins produced have molecular weights of at least about 7500 Daltons. Furthermore, the invention discusses the use of these glycosylated proteins in the assembly of amperometric biosensors.
Career Highlights
Throughout his career, Branden has worked with various companies, including Design-Zyme LLC. His expertise in glycosylation has positioned him as a key figure in the field, contributing to advancements in protein engineering and biosensor technology.
Collaborations
Branden has collaborated with notable individuals such as Peter Albert Petillo and Dwight O'Dell Deay, III. These collaborations have further enriched his work and expanded the impact of his inventions.
Conclusion
Michael Gregory Branden is a notable inventor whose work in glycosylation methods has the potential to revolutionize the production and application of glycosylated proteins. His contributions are significant in advancing both scientific understanding and practical applications in biotechnology.