Company Filing History:
Years Active: 2015
Title: Michael Gaston Joseph Grandgeorge: Innovator in Recombinant Albumin Purification
Introduction
Michael Gaston Joseph Grandgeorge is a notable inventor based in Lyons, France, recognized for his contributions to the fields of biochemistry and pharmaceutical development. His work primarily focuses on the purification of recombinant albumin, a vital protein used in various medical applications. With a singular patent to his name, Grandgeorge exemplifies the innovative spirit of modern scientific research.
Latest Patents
Grandgeorge holds a patent titled "Process for the Purification of Recombinant Albumin." This groundbreaking process enables the preparation of a highly pure albumin solution. The method involves subjecting albumin, preferably expressed and secreted by transformed yeast, to a meticulous series of chromatographic steps. These steps include positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography using immobilized aminophenylboronic acid, negative mode cation exchange chromatography, and further negative or positive mode anion exchange chromatography. Additionally, the patent discloses a process for reducing the level of nickel in the albumin solution and includes a recombinant albumin coding sequence with multiple in-frame translation stop codons.
Career Highlights
Michael Grandgeorge is associated with Novozymes Biopharma DK A/S, a company renowned for its advancements in enzyme and protein-based solutions. His expertise in recombinant protein purification has positioned him as a valuable asset in the biomedical field. Through his innovative work, he has paved the way for improved therapeutic applications of albumin, which is crucial for numerous clinical treatments.
Collaborations
During his career, Grandgeorge has collaborated with esteemed colleagues such as Hendrik Van Urk and Philip Harvey Morton. These collaborations have likely contributed to the development and refinement of his patent, highlighting the importance of teamwork and expertise-sharing in the pursuit of scientific advancement.
Conclusion
Michael Gaston Joseph Grandgeorge's innovative work in the purification of recombinant albumin signifies a notable achievement in biochemistry. With his patent capturing an essential process for obtaining high-purity albumin solutions, he continues to contribute to the scientific community. As modern medicine increasingly relies on recombinant proteins, Grandgeorge’s advancements may lead to significant improvements in therapeutic applications, affirming the importance of innovation in our health care systems.