Company Filing History:
Years Active: 1981-1982
Title: Innovations by Inventor Michael D. Tufano in Chromatography
Introduction: Michael D. Tufano, an accomplished inventor based in Broadview, IL, has made significant contributions to the field of chromatography, holding a total of four patents. His work focuses primarily on the resolution of racemates through the development of advanced chiral supports.
Latest Patents: Among his latest patents, Tufano has introduced innovative chiral supports designed for the resolution of racemic mixtures. One notable invention features an inorganic oxide impregnated with poly(aminostyrene), where amino groups are covalently bonded to the carboxyl groups of chiral organic hydroxy acids. This creation serves as an effective solid stationary phase for chromatographic separation. Another patent involves a material that can function as the stationary phase in liquid-solid chromatography. This material consists of an inorganic oxide that has been silylated with a reagent, whose remaining terminus is covalently bonded to a chiral hydroxy acid. For instance, a 3-aminopropylsilylated silica gel may be treated with a chiral tartaric anhydride to establish a carboxamide linkage, effectively binding the chiral acid to the support.
Career Highlights: Michael D. Tufano's professional journey has been marked by his association with the company UOP LLC, where he has pursued his research and development endeavors. His innovative approaches and dedication have been recognized through the patents he has secured, reflecting his expertise in the area of chromatography.
Collaborations: Throughout his career, Tufano has collaborated with esteemed colleagues, including Thomas P. Malloy and Ted Symon. These partnerships have contributed positively to his research efforts, enhancing the development of novel inventions in his field.
Conclusion: Michael D. Tufano's inventive spirit and commitment to advancing chromatography technology through his patents make him a notable figure in the field. His innovative chiral supports for resolving racemates not only showcase his talent as an inventor but also promise to have significant impacts on the scientific community and industry applications.