Company Filing History:
12 out of 59 
1 out of 832,680 Years Active: 2002-2022
Title: Michael Comb - Innovator in Antibody Development
Introduction
Michael Comb is an accomplished inventor based in Manchester, MA, with a remarkable portfolio featuring 13 patents. His work primarily focuses on the development of innovative antibodies that target specific modifications in proteins, significantly advancing the field of proteomics.
Latest Patents
Among his latest patents is a groundbreaking invention regarding motif-specific and context-independent antibodies. These antibodies are designed to bind specifically to a modified motif involving sumoylated lysine residues and a C-terminal aspartic acid residue. This invention has wide applications in identifying recurring motifs in a variety of non-homologous peptides and proteins across different organisms. Additionally, Comb has developed innovative antibody reagents that selectively bind to ubiquitinated polypeptides, facilitating the identification of ubiquitination sites through proteomic analysis using mass spectrometry. These reagents exhibit a unique context-independent affinity for ubiquitin remnants, enhancing their utility in protein analysis.
Career Highlights
Michael Comb has made significant contributions to the fields of biochemistry and molecular biology. Throughout his career, he has been associated with prominent companies like Cell Signaling Technology, Inc. His expertise has led to numerous advancements in the understanding and analysis of post-translational modifications, particularly in ubiquitination and sumoylation.
Collaborations
During his professional journey, Comb has collaborated with notable colleagues such as Yi Tan and Hui Zhang. These partnerships have fostered a rich exchange of ideas and innovations, contributing to the successful development of his inventions.
Conclusion
Michael Comb's inventive work continues to push the boundaries of biochemistry, particularly in the realm of antibody development. His patents not only showcase his inventive prowess but also play a crucial role in advancing research in proteomics, benefiting scientists and researchers worldwide.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.