Location History:
- Edmonds, WA (US) (1991 - 1995)
- Seattle, WA (US) (1993 - 1995)
Company Filing History:
Years Active: 1991-1995
Title: Michael C Deeley: Innovator in Biotechnology
Introduction
Michael C Deeley is a prominent inventor based in Seattle, WA (US). He has made significant contributions to the field of biotechnology, particularly in the development of human colony-stimulating factors. With a total of 5 patents to his name, Deeley has established himself as a key figure in his area of expertise.
Latest Patents
Among his latest patents is a DNA sequence encoding nonglycosylated analogs of human colony-stimulating factor. This invention discloses an analog human colony-stimulating factor (hCSF) that comprises a mutant amino acid sequence substantially homologous to the native sequence of an hCSF. The mutant sequence includes at least one amino acid substitution, deletion, or insertion that inactivates the N-glycosylation site. Another notable patent involves analogs of human granulocyte-macrophage colony-stimulating factor. This innovation achieves amplified expression of recombinant DNA products in hosts that express proteases cleaving at multi-basic amino acid residues. The cDNAs encoding granulocyte-macrophage colony-stimulating factor (GM-CSF) are mutated to delete or replace one or both of the arginine residues at positions 23 and 24, while maintaining the activity of the wild-type protein.
Career Highlights
Michael C Deeley has had a distinguished career, working at Immunex Corporation, where he has been able to apply his innovative ideas in a practical setting. His work has contributed to advancements in therapeutic applications, particularly in the treatment of various medical conditions.
Collaborations
Throughout his career, Deeley has collaborated with notable colleagues, including Virginia L Price and David L Urdal. These collaborations have further enhanced his research and development efforts in biotechnology.
Conclusion
Michael C Deeley is a notable inventor whose work in biotechnology has led to significant advancements in human colony-stimulating factors. His contributions continue to impact the field positively, showcasing the importance of innovation in medical research.