Company Filing History:
Years Active: 1992-1997
Title: Michael B Bolger: Innovator in Allosteric Modulation
Introduction
Michael B Bolger is a notable inventor based in Los Alamitos, CA (US). He has made significant contributions to the field of pharmacology, particularly in the area of allosteric modulation. With a total of 5 patents to his name, Bolger's work focuses on innovative methods and compositions that address various neurological conditions.
Latest Patents
Among his latest patents, Bolger has developed methods, compositions, and compounds for allosteric modulation of the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex. This invention aims to modulate brain excitability to alleviate stress, anxiety, insomnia, and seizure activity using specific steroid derivatives. Additionally, he has created a method for making 3.alpha.-hydroxy, 3.beta.-substituted-pregnanes. This invention simplifies the conversion of pregnan-3,20-dione compounds to the desired form through selective use of reagents, allowing for stereo-specific modifications.
Career Highlights
Bolger has worked with prestigious institutions, including the University of Southern California and Cocensys Inc. His experience in these organizations has contributed to his expertise in the field of pharmacology and innovation.
Collaborations
Some of his notable coworkers include Kelvin W Gee and Nancy C Lan. Their collaborative efforts have further advanced the research and development of his patented technologies.
Conclusion
Michael B Bolger's innovative work in allosteric modulation and his contributions to pharmacology highlight his role as a significant inventor in the field. His patents reflect a commitment to addressing critical neurological issues through scientific advancement.