Company Filing History:
Years Active: 2010-2013
Title: Michael Anthony Tangrea: Innovator in Target Activated Microtransfer
Introduction
Michael Anthony Tangrea is a notable inventor based in Odenton, MD (US). He has made significant contributions to the field of biological sample processing, holding a total of 5 patents. His innovative work focuses on methods and devices that enhance the separation of targets from biological samples.
Latest Patents
One of Tangrea's latest patents is titled "Target Activated Microtransfer." This invention describes a method for removing a target from a biological sample by placing a transfer surface in contact with the sample. The transfer surface is then focally altered to allow selective separation of the target, which can be a cell or cellular component. The process involves activating the transfer surface from within the target, such as by heating it to adhere to a thermoplastic transfer surface. This method can be enhanced by using immunoreagents that specifically bind to the target, allowing for precise separation and transfer of the target from the tissue section.
Another aspect of his invention includes a device designed for performing target activated transfer. This device features a mounting surface for tissue samples and a light source that uniformly irradiates both stained and unstained regions of the tissue. The system is automated, ensuring efficient transfer of tissue from the sample to a transfer substrate.
Career Highlights
Michael Anthony Tangrea is currently employed at the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution allows him to contribute to advancements in medical research and technology.
Collaborations
Throughout his career, Tangrea has collaborated with esteemed colleagues, including Michael R Emmert-Buck and Rodrigo F Chuaqui. These collaborations have further enriched his research and innovation efforts.
Conclusion
Michael Anthony Tangrea's contributions to the field of biological sample processing through his patents and work at the National Institutes of Health highlight his role as a significant innovator. His inventions, particularly in target activated microtransfer, demonstrate the potential for advancements in medical research and applications.