Oakland, CA, United States of America

Michael A Siani


Average Co-Inventor Count = 3.4

ph-index = 4

Forward Citations = 166(Granted Patents)


Location History:

  • Oakland, CA (US) (1993 - 1998)
  • San Francisco, CA (US) (2005 - 2010)

Company Filing History:


Years Active: 1993-2010

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6 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Michael A. Siani

Introduction

Michael A. Siani is a notable inventor based in Oakland, California, recognized for his significant contributions to the field of biotechnology. With a total of six patents to his name, Siani has made strides in the computational analysis of polyketides and the design of polyketide synthase genes. His work has implications for various applications in the biotechnology sector.

Latest Patents

Siani's latest patents include innovative methods for the computational analysis of polyketides. These methods facilitate the computer-assisted design of PKS genes by representing the structure of a polyketide and/or a PKS gene using alphanumeric symbols. This representation allows for efficient computer-assisted analysis. Additionally, he has developed a database of polyketides and corresponding PKS genes that can be rapidly searched, enabling the design and specification of PKS genes through the recombination of modules from existing PKS genes. Another significant patent involves the creation of novel proteins and protein libraries. These proteins contain functional modules derived from different parent protein molecules, exemplified by cross-over chemokines that combine peptide segments from RANTES, SDS-1, vMIP-I, and vMIP-II. The resulting proteins and libraries are highly pure and suitable for diagnostic and high-throughput screening assays.

Career Highlights

Throughout his career, Siani has worked with prominent companies in the biotechnology field, including Chiron Corporation and Gryphon Therapeutics, Inc. His experience in these organizations has contributed to his expertise and innovative capabilities in the industry.

Collaborations

Siani has collaborated with notable individuals in his field, including Daniel V. Santi and Ronald N. Zuckermann. These collaborations have likely enriched his research and development efforts.

Conclusion

Michael A. Siani's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the field, paving the way for future innovations in the design and analysis of polyketides.

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