Company Filing History:
1 out of 32 
2 out of 832,912 Years Active: 2016-2020
Title: Michael A Kennedy: Innovator in Cancer Treatment
Introduction
Michael A Kennedy is a notable inventor based in Oxford, OH (US), recognized for his contributions to cancer treatment through innovative technologies. He holds a total of 3 patents that focus on engineered oncolytic viruses and DNA aptamers aimed at enhancing chemotherapy efficacy.
Latest Patents
Kennedy's latest patents include groundbreaking work on engineered oncolytic viruses that contain hyper-binding sites to sequester and suppress the activity of oncogenic transcription factors. This invention provides novel artificial, non-naturally-occurring double-stranded DNA segments capable of acting as decoy binding sites for oncogenic transcription factors. The method aims to suppress aberrant activity that promotes cancer progression. By introducing these engineered transcription factor binding sites into cells using oncolytic viruses, the invention seeks to competitively sequester oncogenic transcription factors away from host genomic DNA, thereby reducing their activity and restoring sensitivity to chemotherapy.
Another significant patent involves the use of HMGA-targeted phosphorothioate DNA aptamers to suppress carcinogenic activity and increase sensitivity to chemotherapy agents in human cancer cells. Elevated expression of high mobility group A (HMGA) protein in human pancreatic cancer cells is correlated with resistance to the chemotherapy agent gemcitabine. Kennedy's invention utilizes HMGA-targeted AT-rich phosphorothioate DNA aptamers to enhance chemotherapy efficacy, particularly in human pancreatic cancer treatment.
Career Highlights
Throughout his career, Michael A Kennedy has made substantial contributions to the field of cancer research and treatment. His innovative approaches have the potential to significantly improve patient outcomes in cancer therapy.
Collaborations
Kennedy has worked with various institutions, including Miami University, to further his research and development in cancer treatment technologies.
Conclusion
Michael A Kennedy's work exemplifies the intersection of innovation and healthcare, particularly in the fight against cancer. His patents reflect a commitment to developing novel solutions that enhance the effectiveness of existing treatments.