Michael A Gelman

Title: Michael A Gelman: Innovator in Anti-Infective Compounds

Introduction

Michael A Gelman is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of anti-infective compounds, holding a total of 8 patents. His work focuses on developing innovative solutions for treating pathogen infections.

Latest Patents

One of Gelman's latest patents involves PI-kinase inhibitors with anti-infective activity. The compounds and methods provided aim to treat various pathogen infections. These anti-infective compounds exhibit broad-spectrum activity against a range of infective diseases. The diseases targeted are caused by pathogens that contain a basic amino acid PIP-2 pincer (BAAPP) domain. This domain interacts with phosphatidylinositol 4,5-bisphosphate (PIP-2) to facilitate pathogen replication. Additionally, the patent outlines methods for inhibiting a PI4-kinase and methods for inhibiting viral infections. Some embodiments of the compound include a PI4-kinase inhibiting compound that is a 5-aryl-thiazole or a 5-heteroaryl-thiazole. The subject compounds may also be formulated in combination with a second anti-infective agent, such as interferon or ribavirin.

Career Highlights

Throughout his career, Michael A Gelman has worked with esteemed institutions, including Leland Stanford Junior University and the University of California. His research has significantly advanced the understanding and treatment of infectious diseases.

Collaborations

Some of his notable coworkers include Jeffrey S Glenn and Brandon Tavshanjian. Their collaborative efforts have contributed to the development of innovative anti-infective strategies.

Conclusion

Michael A Gelman is a distinguished inventor whose work in anti-infective compounds has the potential to impact the treatment of infectious diseases significantly. His contributions to the field are noteworthy and continue to inspire future innovations.