Company Filing History:
Years Active: 2023
Title: Mert Karaoglan: Innovator in Synthetic Promoter Design
Introduction
Mert Karaoglan is a notable inventor based in Erzincan, Turkey. He has made significant contributions to the field of biotechnology, particularly in the area of synthetic promoter design for recombinant protein production. His innovative work has led to the development of a patent that enhances the understanding and application of regulatory DNA regions.
Latest Patents
Karaoglan holds a patent titled "Determination of regulatory DNA regions of alcohol dehydrogenase 3 (ADH3) promoter and design of synthetic promoters for recombinant protein production." This invention focuses on the ADH3 promoter and includes polynucleotide sequences, vectors, and expression cassettes that encompass DNA regions responsible for regulating the ADH3 promoter. The research involved deletion analyses in the ADH3 promoter to identify regions that influence promoter strength. Notably, the deletion of nucleotides between 539 and 638 resulted in a remarkable 63% increase in ADH3 promoter activity. Furthermore, five different synthetic promoters were created using the identified positive regulatory regions, achieving promoter activities ranging from approximately 165% to 200%.
Career Highlights
Mert Karaoglan is affiliated with Akdeniz Universitesi, where he continues to advance his research in biotechnology. His work not only contributes to academic knowledge but also has practical implications in the field of protein production.
Collaborations
Karaoglan has collaborated with notable colleagues, including Mehmet Inan and Fidan Erden Karaoglan. Their joint efforts have further enriched the research landscape in synthetic biology.
Conclusion
Mert Karaoglan's innovative contributions to the field of synthetic promoter design exemplify the potential of biotechnology in enhancing recombinant protein production. His patent and ongoing research efforts are paving the way for future advancements in this critical area.