Location History:
- Lecco, IT (2004)
- Cremella Lecco, IT (2004 - 2007)
Company Filing History:
2 out of 505 
1 out of 26 
Years Active: 2004-2007
Title: Merli Valeriano: Innovator in Pharmaceutical Chemistry
Introduction
Merli Valeriano is a notable inventor based in Cremella Lecco, Italy. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the area of enantiomer separation and racemization processes.
Latest Patents
Valeriano holds three patents, with his latest focusing on the racemization and enantiomer separation of clopidogrel. The processes he developed involve separating the enantiomers by crystallizing the (S) enantiomer as a camphor sulfonate salt from a hydrocarbon or a mixture of a hydrocarbon and a co-solvent, preferably DMF:toluene. The (R) enantiomer is then racemized and recycled through a reaction with a catalytic amount of a base, preferably t-butoxide.
Career Highlights
Throughout his career, Valeriano has worked with prominent companies in the pharmaceutical industry, including Teva Pharmaceutical Industries Limited and Teva Gyógyszergyár Zártkörűen Működő Részvénytársaság. His work has significantly impacted the development of pharmaceutical processes and products.
Collaborations
Valeriano has collaborated with several professionals in his field, including Paola Daverio and Stefano Bianchi. These collaborations have contributed to the advancement of his research and innovations.
Conclusion
Merli Valeriano's work in the field of pharmaceutical chemistry, particularly in the separation and racemization of clopidogrel, showcases his innovative spirit and dedication to advancing medical science. His contributions continue to influence the industry and improve pharmaceutical processes.