Guangdong, China

Mengyun Zhang



Average Co-Inventor Count = 7.5

ph-index = 1

Forward Citations = 2(Granted Patents)


Location History:

  • Guangzhou, CN (2019)
  • Guangdong, CN (2022)

Company Filing History:


Years Active: 2019-2022

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2 patents (USPTO):Explore Patents

Title: Innovations of Mengyun Zhang in Stem Cell Research

Introduction

Mengyun Zhang is a prominent inventor based in Guangdong, China. He has made significant contributions to the field of stem cell research, particularly in the differentiation of pluripotent stem cells into T cells. His innovative work has led to the development of methods that hold promise for therapeutic applications.

Latest Patents

Mengyun Zhang holds 2 patents that focus on groundbreaking advancements in stem cell technology. His latest patents include:

1. **Pluripotent stem cell and T cell differentiated therefrom and application thereof**: This invention provides a pluripotent stem cell that comprises a co-expression vector in which Runx1 and Hoxa9 are expressed in tandem. The method successfully establishes pluripotent stem cells that inducibly co-express exogenous Runx1 and Hoxa9. These cells are then directionally differentiated into T-lineage progenitor cells, ultimately developing into functional T cells without tumorigenic risk.

2. **Method for regenerating T cells and applications thereof**: This patent describes a method for inducing the transdifferentiation of B lymphoid cells into T lymphoid cells using the transcription factor Hoxb5. The process involves introducing Hoxb5 into B lymphoid cells to obtain cells that overexpress Hoxb5. These cells are then implanted into a subject's body to regenerate T cell progenitor cells, which differentiate into mature T cells that are functionally normal and exhibit low tumorigenesis risk.

Career Highlights

Mengyun Zhang is affiliated with the Chinese Academy of Sciences, where he conducts his research. His work has garnered attention for its potential applications in regenerative medicine and immunotherapy.

Collaborations

He collaborates with notable colleagues, including Jinyong Wang and Cui Lv, who contribute to his research endeavors.

Conclusion

Mengyun Zhang's innovative patents and research in stem cell technology represent significant advancements in the field. His work not only enhances our understanding of stem cell differentiation but also opens new avenues for therapeutic applications in medicine.

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