This inventor holds 3 USPTO granted patents and 2 published patent applications. Top assignee: Yale University. Active years: 2025.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2025
Title: Mengwen Zhang: Innovator in Protein Degradation Technologies
Introduction
Mengwen Zhang is a prominent inventor based in New Haven, CT (US). He has made significant contributions to the field of biochemistry, particularly in the development of small molecules aimed at targeting the selective degradation of circulating proteins. With a total of 3 patents, his work is paving the way for innovative therapeutic approaches.
Latest Patents
One of Mengwen Zhang's latest patents is focused on bifunctional small molecules designed to target the selective degradation of circulating proteins. This invention involves small molecules that contain a circulating protein binding moiety (CPBM) linked to a cellular receptor binding moiety (CRBM). The CRBM is a membrane receptor of degrading cells, such as hepatocytes. These compounds can be utilized to treat various disease states by facilitating the removal of circulating proteins through degradation in the hepatocytes or macrophages of patients in need of therapy.
Another significant patent involves compositions and methods for the enrichment and detection of ubiquitin and ubiquitin conjugates. This invention describes synthetic peptides that include a high-affinity ubiquitin binding domain, which can be coupled to materials like resins and dyes for effective detection of ubiquitination in samples.
Career Highlights
Mengwen Zhang is affiliated with Yale University, where he continues to advance research in his field. His innovative work has garnered attention and respect within the scientific community, contributing to the understanding of protein degradation mechanisms.
Collaborations
Throughout his career, Mengwen Zhang has collaborated with notable colleagues, including Jason Berk and Mark Hochstrasser. These partnerships have further enriched his research and expanded the impact of his inventions.
Conclusion
Mengwen Zhang's contributions to the field of protein degradation technologies highlight his role as an influential inventor. His innovative patents and collaborations reflect a commitment to advancing therapeutic solutions for various diseases.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile