Mendi A Higgins

Title: Mendi A Higgins: Innovator in Pharmaceutical Chemistry

Introduction

Mendi A Higgins is a prominent inventor based in Meriden, CT (US). She has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds that target integrins. With a total of 9 patents to her name, Higgins has established herself as a key figure in her industry.

Latest Patents

Among her latest patents, Higgins has developed indazole derivatives as alpha v integrin antagonists. These compounds, represented by Formula (Ia) or (Ib), include stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates. The compounds serve as antagonists to αV-containing integrins and are associated with various medical applications. This invention also encompasses pharmaceutical compositions that utilize these compounds for treating diseases related to dysregulation of αV-containing integrins, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders.

Career Highlights

Higgins is currently employed at Bristol-Myers Squibb Company, where she continues to innovate and contribute to the advancement of pharmaceutical science. Her work has been instrumental in developing new therapeutic options for patients suffering from complex medical conditions.

Collaborations

Throughout her career, Higgins has collaborated with notable colleagues, including Lawrence R Marcin and Graham S Poindexter. These partnerships have enhanced her research and contributed to the successful development of her patented inventions.

Conclusion

Mendi A Higgins is a trailblazer in the field of pharmaceutical chemistry, with a focus on integrin antagonists. Her innovative work and collaborations have the potential to significantly impact the treatment of various diseases.