Melvin Little

Title: Melvin Little: Innovator in Immunotherapy

Introduction

Melvin Little is a notable inventor based in Neckargemund, Germany. He has made significant contributions to the field of immunotherapy, particularly through his innovative work on antibodies.

Latest Patents

Melvin Little holds a patent for a "Human CD3-specific antibody with immunosuppressive properties." This patent describes mono- and multivalent scFv-antibodies that specifically bind to the human T cell marker CD3. These antibodies exhibit strong immunosuppressive effects without causing a significant release of cytokines. Additionally, the patent includes polynucleotides encoding these antibodies, vectors containing said polynucleotides, and host cells transformed with them. The pharmaceutical compositions derived from this work are particularly useful for immunotherapy, especially in preventing acute transplant rejections.

Career Highlights

Melvin Little is associated with Affimed GmbH, a company that focuses on developing innovative immunotherapies. His work has positioned him as a key figure in advancing therapeutic strategies that leverage the immune system.

Collaborations

Some of his notable coworkers include Fabrice Le Gall and Sergey Kipriyanov, who have collaborated with him on various projects within the field of immunotherapy.

Conclusion

Melvin Little's contributions to immunotherapy through his patented innovations highlight the importance of research in developing effective treatments for transplant rejections. His work continues to influence the field and pave the way for future advancements.