Company Filing History:
Years Active: 2014-2025
Title: Innovations by Melissa Heitmann
Introduction
Melissa Heitmann is a notable inventor based in Hopewell Junction, NY (US). She has made significant contributions to the field of chemistry, particularly in the synthesis of diketopiperazines. With a total of six patents to her name, her work has advanced the methods used in this area of research.
Latest Patents
One of her latest patents focuses on the formation of N-protected 3,6-bis-(4-aminoalkyl)-2,5-diketopiperazine. The disclosed embodiments detail improved methods for the synthesis of diketopiperazines from amino acids. In particular, these methods enhance the cyclocondensation and purification of N-protected 3,6-(aminoalkyl)-2,5-diketopiperazines from N-protected amino acids. The patent describes methods for synthesizing 3,6-bis-[N-protected aminoalkyl]-2,5-diketopiperazine by heating a mixture of an amino acid in the presence of a catalyst in an organic solvent. The catalysts include sulfuric acid, phosphoric acid, p-toluenesulfonic acid, and others. The solvents used in the process comprise dimethylacetamide, N-methyl-2-pyrrolidone, and various glymes, among others.
Career Highlights
Melissa Heitmann is currently associated with Mannkind Corporation, where she continues to innovate in her field. Her work has been instrumental in developing new methodologies that enhance the efficiency and effectiveness of chemical synthesis.
Collaborations
Some of her notable coworkers include John J Freeman and Adrienne Stamper, who have collaborated with her on various projects.
Conclusion
Melissa Heitmann's contributions to the field of chemistry through her patents and innovative methods have made a significant impact. Her work continues to influence the synthesis of diketopiperazines and showcases her dedication to advancing scientific research.