New York, NY, United States of America

Melissa H Wrzeszczynska


Average Co-Inventor Count = 4.0

ph-index = 2

Forward Citations = 8(Granted Patents)


Company Filing History:


Years Active: 2001-2007

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4 patents (USPTO):Explore Patents

Title: Innovations of Melissa H Wrzeszczynska

Introduction

Melissa H Wrzeszczynska is a prominent inventor based in New York, NY (US). She has made significant contributions to the field of gene regulation through her innovative research and inventions. With a total of four patents to her name, her work focuses on the interactions of transcription factors and their implications for cellular transformation.

Latest Patents

One of her latest patents is titled "Methods for identifying modulators of transcriptional activator protein interactions." This invention relates to methods for identifying interacting regions of transcription factors and agents that modulate these interactions. The findings indicate that specific sites within residues 130–154 and 343–358 in Stat3 interact with the transcription factor c-Jun. Additionally, on c-Jun, a site within residues 105 and 334, particularly between residues 105 and 263, interacts with Stat3. These interactions allow for the identification of agents that can modulate the interaction between these transcription factors, thereby influencing gene transcription.

Another notable patent is "Stat3 protein fragments and mutants," which also focuses on identifying interacting regions of transcription factors and agents that modulate these interactions. The insights gained from this research are crucial for understanding gene regulation and its potential applications in cellular transformation.

Career Highlights

Melissa H Wrzeszczynska is affiliated with The Rockefeller University, where she conducts her research. Her work has garnered attention for its innovative approach to understanding the complexities of gene regulation.

Collaborations

Throughout her career, she has collaborated with esteemed colleagues such as James E Darnell, Jr. and Xiaokui Zhang. These collaborations have further enriched her research and contributed to the advancement of knowledge in her field.

Conclusion

Melissa H Wrzeszczynska's contributions to the field of gene regulation through her patents and research are noteworthy. Her innovative methods for identifying transcription factor interactions have significant implications for understanding cellular processes. Her work continues to inspire advancements in the scientific community.

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