Melissa E Winn

Title: Innovations and Contributions of Inventor Melissa E. Winn

Introduction

Melissa E. Winn is a prominent inventor based in Rockville, MD (US), known for her significant contributions to the field of biotechnology. With a total of eight patents to her name, she has made remarkable advancements in the understanding and application of human secretoglobin proteins. Her work has the potential to impact various medical conditions and improve patient outcomes.

Latest Patents

One of her latest patents focuses on the modification and compositions of human secretoglobin proteins. This innovation involves the generation of novel compositions of recombinant human CC10 protein through chemical modifications. These new synthetic preparations contain isoforms of chemically modified rhCC10, characterized by enhanced or altered biological properties compared to the unmodified protein. Such preparations may serve as standards for identifying naturally occurring isoforms of native CC10 protein from blood or urine, ultimately aiding in the measurement of new CC10-based biomarkers to assess patient disease status. Additionally, these preparations may be utilized to treat respiratory, autoimmune, inflammatory, and other medical conditions that are not effectively addressed by the unmodified protein.

Another significant patent by Melissa E. Winn involves compositions and methods of use for secretoglobins to protect the glycocalyx via interactions with heparan sulfate proteoglycan proteins. This patent provides SCGB-based preparations and methods to protect the glycocalyx in medical, veterinary, and cosmetic applications. The glycocalyx is a protective layer surrounding all cells, and SCGBs interact with heparan sulfate proteoglycan proteins to modulate cell signaling and cellular responses to external factors.

Career Highlights

Throughout her career, Melissa has worked with notable companies such as Apc Research Assets, LLC and Therabron Therapeutics, Inc. Her innovative research and development efforts have positioned her as a leader in her field, contributing to advancements in therapeutic applications.

Collaborations

Melissa has collaborated with esteemed colleagues, including Aprile L. Pilon and Humcha K. Hariprakasha. These partnerships have further enhanced her research and the impact of her inventions.

Conclusion

Melissa E. Winn's contributions to biotechnology through her patents and innovative research have the potential to transform medical treatments and improve patient care. Her work exemplifies the importance of innovation in addressing complex health challenges.