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Title: Melike Lakadamyali: Innovator in Chromatin Detection Methods
Introduction
Melike Lakadamyali is a prominent inventor based in Castelldefels-Barcelona, Spain. He has made significant contributions to the field of cellular biology, particularly in the detection of chromatin states. His innovative approach has the potential to advance our understanding of cellular mechanisms and their implications in various biological processes.
Latest Patents
Lakadamyali holds a patent for a method that focuses on detecting the chromatin state of a cell. The invention involves recording a super-resolution image of nucleosome organization and correlating this image with the size of nucleosomal clutches, nucleosomal density, and the number of nucleosomes per nucleosomal clutch. Additionally, the patent includes a kit that comprises a first antibody capable of specifically binding to a histone protein and a photoswitchable fluorophore-linked secondary antibody. This kit is designed for detecting the chromatin state of a cell and isolating cells in either an open or closed chromatin state. The invention also encompasses a device adapted to detect the chromatin state of a cell.
Career Highlights
Throughout his career, Lakadamyali has worked with notable organizations, including the Fundació Institut De Ciències Fotóneques and the Fundació Centre De Regulació Genomica. His work in these institutions has allowed him to explore and develop innovative techniques in the realm of cellular detection.
Collaborations
Lakadamyali has collaborated with esteemed colleagues, including Carlo Manzo and Maria Aurelia Ricci. These partnerships have contributed to the advancement of his research and the successful development of his patented methods.
Conclusion
Melike Lakadamyali's contributions to the field of chromatin detection represent a significant advancement in cellular biology. His innovative methods and collaborative efforts continue to pave the way for future research and applications in this vital area of study.
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