Meisen Liu

Title: Meisen Liu: Innovator in Synthetic Nicotine Production

Introduction

Meisen Liu is a prominent inventor based in Guangdong, China. He has made significant contributions to the field of synthetic nicotine production, holding a total of 3 patents. His innovative methods have the potential to impact the pharmaceutical and tobacco industries.

Latest Patents

Liu's latest patents include a preparation method of racemic nicotine. This method involves several steps, starting with the reaction of nicotinyl chloride and methylamine under alkaline conditions to produce methylnicotinamide. This compound is then condensed with monochloroacetone to yield N-methyl-N-(2-oxopropyl) nicotinamide. Following this, a self-aldol condensation leads to the formation of 1-methyl-5-(pyridin-3-yl)-1,2-dihydro-3H-pyrrol-3-one, which is finally reduced to obtain racemic nicotine. Another notable patent is a method for preparing chiral synthetic nicotine. This process includes condensing nicotinic acid ester and γ-butyrolactone, performing a ring-opening reaction, and separating various compounds to ultimately produce chiral nicotine.

Career Highlights

Meisen Liu is currently employed at Shenzhen Zinwi Bio-tech Co., Ltd. His work at this company focuses on advancing the methods of nicotine synthesis, contributing to the development of safer and more effective nicotine products. Liu's expertise in this area has positioned him as a key figure in the field of biochemistry and pharmacology.

Collaborations

Liu collaborates with several talented individuals, including Jun Zou and Yang Zou. Their combined efforts enhance the research and development capabilities within their organization, fostering innovation in synthetic methodologies.

Conclusion

Meisen Liu's contributions to the field of synthetic nicotine production are noteworthy. His innovative patents and collaborative efforts continue to drive advancements in this important area of research.