Mehran Pazirandeh

Title: Innovations of Mehran Pazirandeh

Introduction

Mehran Pazirandeh is an accomplished inventor based in Silver Spring, MD (US). He holds 2 patents that showcase his contributions to the field of biotechnology and environmental science. His work focuses on innovative methods for addressing critical challenges, particularly in the areas of enzyme modification and heavy metal removal.

Latest Patents

One of his latest patents is titled "Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles." This invention involves modifying enzymes to incorporate anchor sites that allow for linking to a target surface without compromising their catalytic activity. A stable carrier is constructed to accommodate and bind the selected enzyme, which is non-covalently linked to the carrier using metal salts of iminodiacetate.

Another significant patent is related to "Bacteria expressing metallothionein gene into the periplasmic space." In this patent, a gene coding for metallothionein expression is incorporated into an expression vehicle, enabling bacteria to express this gene into their periplasmic space. This method may allow for multiple copies of the metallothionein gene to be incorporated within a single bacterium. A typical expression vehicle used is a p-MalP plasmid, which facilitates the expression of metallothionein as a fusion product with proteins like maltose-binding protein. The resulting device can effectively remove heavy metals from aqueous media.

Career Highlights

Mehran Pazirandeh has worked with notable organizations, including the United States Navy and the United States of America as represented by the Secretary of the Navy. His work has significantly contributed to advancements in environmental biotechnology and public safety.

Collaborations

Throughout his career, Pazirandeh has collaborated with esteemed colleagues such as James R. Campbell and Alok Singh. These partnerships have fostered innovation and enhanced the impact of his research.

Conclusion

Mehran Pazirandeh's innovative patents and collaborations highlight his significant contributions to biotechnology and environmental science. His work continues to pave the way for advancements in enzyme technology and heavy metal remediation.