Location History:
- Charlestown, MA (US) (1996 - 2009)
- Boston, MA (US) (1997 - 2011)
- Bronx, NY (US) (2018)
- New York, NY (US) (2022)
Company Filing History:
19 out of 2,886 
2 out of 389 
2 out of 2,488 
Years Active: 1996-2022
Title: Innovations in Genetic Modification by Megan Sykes
Introduction
Megan Sykes, based in Charlestown, MA, has made significant contributions to the field of biomedical engineering through her innovative inventions. With an impressive portfolio of 20 patents, she is renowned for her pioneering work in genetic modification and xenotransplantation.
Latest Patents
Megan Sykes holds several groundbreaking patents, including her recent inventions focused on genetic modification of pigs for xenotransplantation. This invention includes the use of transgenic donor animals designed to enhance the long-term survival of their cells, tissues, and organs when transplanted into human patients. By utilizing a 'genetic switch', the transgenic animals maintain their health while simultaneously optimizing the expression of human transgenes for improved transplant tolerance.
Another notable patent is focused on the generation of autologous T-cells in mice. This invention offers a novel animal model and methods for producing large quantities of diverse and functional naive T cells, which are derived from the bone marrow of adult donors. These developments are crucial in advancing research and therapy in immunology and transplantation.
Career Highlights
Throughout her career, Megan Sykes has been associated with leading organizations, including The General Hospital Corporation and Genetics Institute, Inc. This experience has bolstered her expertise in biomedical research and enhanced her reputation as a leader in genetic modification.
Collaborations
Megan has collaborated with other prominent researchers such as Thomas R. Spitzer and David H. Sachs. These collaborations have contributed to her innovative approaches and have led to significant advancements in the fields of transplantation and immunology.
Conclusion
Megan Sykes continues to push the boundaries of science with her significant patents and collaborations. Her work not only enhances our understanding of genetic modification and xenotransplantation but also paves the way for more effective treatments in the future.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.