Company Filing History:

8 out of 656

Chiron Corporation

patents

2 out of 28

Cetus Oncology Corporation

patents

Years Active: 1995-2001

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10 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 6204020 - DNA encoding N∇2 CSF-1 (short form) and carboxy truncated fragment thereof (2001-03-20),

2. 6156300 - Point mutants of N.gradient.2 CSF-1 and carboxy truncated fragments (2000-12-05),

3. 6146851 - DNA encoding NV2 (long form) and carboxy truncated fragments thereof (2000-11-14),

4. 6117422 - N.gradient.2-CSF-1(long form) and carboxy truncated fragments thereof (2000-09-12),

5. 6103224 - N.gradient.2 CSF-1 (short form) and carboxy truncated fragments thereof (2000-08-15),

6. 5681719 - DNA encoding N- and C- terminally truncated colony stimulating factor-1 (1997-10-28),

7. 5672343 - N- 3 deletion mutants of the long form of CSF-1 (1997-09-30),

8. 5643563 - N-.gradient.3 deletion mutants of the short form of CSF-1 (1997-07-01),

9. 5573930 - DNA encoding various forms of colony stimulating factor-1 (1996-11-12),

10. 5470569 - Recombinant colony stimulating factor-1 (1995-11-28),

Title: The Innovative Contributions of Mazie Yee Coyne

Introduction

Mazie Yee Coyne is a notable inventor based in Danville, CA, who has made significant contributions to the field of biotechnology. With a total of 10 patents to her name, she has focused her research on colony stimulating factors and their applications in regulating the immune system.

Latest Patents

Among her latest patents are innovations related to DNA encoding N∇2 CSF-1 and carboxy truncated fragments thereof. These patents describe a colony stimulating factor, CSF-1, which is a lymphokine useful in overcoming immunosuppression induced by chemotherapy or other causes. CSF-1 can be obtained in usable amounts through recombinant methods, including the cloning and expression of murine and human DNA sequences encoding this protein. Both "long" and "short" forms of this protein, as well as muteins corresponding to the cDNA-encoded forms, are disclosed in her patents.

Career Highlights

Mazie has worked with prominent companies in the biotechnology sector, including Chiron Corporation and Cetus Oncology Corporation. Her work has significantly advanced the understanding and application of immune system regulation.

Collaborations

Mazie has collaborated with esteemed colleagues such as Martha B. Ladner and Ernest S. Kawasaki, contributing to a rich exchange of ideas and innovations in her field.

Conclusion

Mazie Yee Coyne's work exemplifies the impact of innovative research in biotechnology, particularly in the development of therapies that enhance immune function. Her contributions continue to influence the landscape of medical science.

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