Maurine E Linder

Title: Maurine E Linder: Innovator in Enzyme Assays

Introduction

Maurine E Linder is a prominent inventor based in Ithaca, NY (US). She has made significant contributions to the field of biochemistry, particularly in the development of methods for enzyme activity screening. Her innovative approach has led to advancements in understanding acyltransferase enzymes.

Latest Patents

Linder holds a patent for a "High-throughput enzyme assay for screening activity of acyltransferases." This method involves preparing a reaction mixture that includes an acyl transferase enzyme, a peptide substrate bound to a fluorophore, an acyl-CoA, and a detergent comprising micelles. The acyl transferase enzyme mediates acylation on a cysteine of the peptide substrate, resulting in an increase in fluorescence polarization. This assay method can also be utilized for screening compounds that may inhibit acyl transferase enzyme activity. She has 1 patent to her name.

Career Highlights

Maurine E Linder is affiliated with Cornell University, where she continues her research and development in enzyme assays. Her work has been instrumental in advancing the understanding of enzyme functions and their applications in various fields.

Collaborations

Linder has collaborated with notable colleagues, including Hening Lin and Jun Young Hong, contributing to her research and the development of innovative methods in her field.

Conclusion

Maurine E Linder's contributions to enzyme assay technology highlight her role as an influential inventor in biochemistry. Her innovative methods pave the way for further research and applications in enzyme activity screening.