Company Filing History:
4 out of 17 
2 out of 111 Years Active: 1992-1998
Title: Maureen A McNally: A Pioneer in Recombinant Adeno-Associated Virus Technology
Introduction
Maureen A McNally is an accomplished inventor based in Palo Alto, California, known for her significant contributions to biotechnology, particularly in the field of recombinant adeno-associated viruses (rAAV). With a total of six patents to her name, McNally's work has advanced methods to produce viral vectors essential for gene therapy and other applications.
Latest Patents
Among her notable patents are innovative methods for producing recombinant adeno-associated virus vectors. These inventions describe simplified techniques using chimeric plasmids that incorporate the Epstein Barr nuclear antigen (EBNA) gene and the latent origin of replication of the Epstein Barr virus (oriP) along with a rAAV genome. The chimeric plasmids are designed to be maintained as multicopy extra-chromosomal elements, particularly in human 293 cells. When induced with wild-type adeno-associated virus helper functions, these permanent cell lines can produce large amounts of rAAV, which are capable of transducing exogenous genes into human cell lines.
Career Highlights
Throughout her career, McNally has made significant strides in the biotechnology sector. She has worked with various prestigious companies, including Applied Immunesciences, Inc. and Rhone-Poulenc Rorer Pharmaceuticals Inc. Her research and inventions have had a lasting impact and continue to be integral in the field of gene therapy.
Collaborations
Collaborating with prominent figures in the field, McNally has worked alongside respected professionals such as Jane S Lebkowski and Thomas B Okarma. These partnerships have further enriched her research and contributed to her innovative findings.
Conclusion
Maureen A McNally's pioneering work in recombinant adeno-associated virus technology has positioned her as a leading inventor in biotechnology. Her patents continue to shape the landscape of gene therapy, demonstrating the importance of innovations in enhancing therapeutic methods and clinical outcomes.
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