Durham, NC, United States of America

Mattia Bonsignori

USPTO Granted Patents = 7 

Average Co-Inventor Count = 4.1

ph-index = 2

Forward Citations = 6(Granted Patents)


Company Filing History:


Years Active: 2019-2024

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7 patents (USPTO):

Title: The Innovative Contributions of Mattia Bonsignori in HIV Research

Introduction: Mattia Bonsignori, an accomplished inventor based in Durham, NC, is known for his significant contributions to the field of HIV research. With a total of seven patents to his name, his work focuses on developing innovative immunogens and methods that could potentially revolutionize HIV therapies.

Latest Patents: Bonsignori's latest patents showcase groundbreaking advancements in immunology. One key patent is centered on compositions comprising HIV envelopes aimed at inducing CH235 lineage antibodies. This invention presents HIV-1 immunogens, including selections from individual CH505, along with methods for swarm immunizations using various combinations of HIV-1 envelopes. Another noteworthy patent involves methods to identify immunogens by targeting improbable mutations. This invention outlines techniques for pinpointing improbable mutations in the heavy or light chain variable domain of antibodies, identifying antigens that bind to these antibodies, and utilizing such antigens to provoke immune responses.

Career Highlights: Throughout his career, Bonsignori has been affiliated with notable organizations. He has held positions at Duke University, where he contributed to advancing scientific research, and at Triad National Security, LLC, where he further applied his innovative ideas to real-world challenges in the realm of health security.

Collaborations: Collaboration has been a key aspect of Bonsignori's research endeavors. He has worked alongside esteemed colleagues such as Barton F. Haynes and Hua-Xin Liao, both of whom share a commitment to improving HIV treatment through rigorous research and development.

Conclusion: Mattia Bonsignori exemplifies the spirit of innovation within the HIV research community. His patents reflect a dedication to not only understanding the complexities of the virus but also to creating practical solutions that could lead to breakthroughs in immunization. As his research continues to evolve, the potential impact of his work on global health remains to be seen.

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