Matthias Loehn

Title: Innovator Matthias Loehn: Pioneering Kinase Inhibitors

Introduction

Matthias Loehn, a prominent inventor based in Frankfurt am Main, Germany, has made remarkable contributions to the field of pharmaceuticals. With a total of 12 patents to his name, Loehn focuses on developing innovative compounds that serve as kinase inhibitors, particularly for treating diabetes and its related complications.

Latest Patents

One of Loehn's recent patents is centered around substituted 6-(4-hydroxy-phenyl)-1H-pyrazolo[3,4-b]pyridine derivatives. This invention concerns pyrazolo[3,4-b]pyridine compounds of the formula I, where various substituents, R, are defined for their structural properties. The compounds serve as significant kinase inhibitors and present a therapeutic avenue for conditions associated with diabetes, including diabetic nephropathy, neuropathy, and retinopathy. Furthermore, the patent outlines their application as active ingredients in pharmaceuticals and related compositions.

Another notable patent by Loehn is for 6-(4-hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives, which also function as kinase inhibitors. This invention similarly targets diseases linked to diabetes, showcasing Loehn's commitment to tackling serious health issues through innovative chemical solutions.

Career Highlights

Throughout his illustrious career, Matthias Loehn has collaborated with major pharmaceutical companies, notably Sanofi and Sanofi-Aventis. His work has not only advanced scientific understanding in his field but has also contributed to pragmatic solutions for significant health challenges associated with diabetes.

Collaborations

Loehn has partnered with fellow researchers and industry professionals, including Oliver Plettenburg and Armin Hofmeister. These collaborations have enriched his research output and widened the scope of his inventions, enabling him to enhance the efficacy of the compounds developed.

Conclusion

Matthias Loehn's innovative work on kinase inhibitors highlights the importance of research and development in improving health outcomes for patients with diabetes. His contributions represent a blend of scientific rigor and practical application, establishing him as a noteworthy figure in the field of pharmaceutical inventions. With a solid foundation of patents, continued research, and meaningful collaborations, Loehn stands at the forefront of innovation aimed at combating complex health issues.