Company Filing History:
Years Active: 2002
Title: The Innovations of Matthias Hoffmann: Pioneering Enzymatic Synthesis
Introduction
Matthias Hoffmann, an inventive researcher based in Weissenfels, Germany, has made significant contributions to the field of biotechnology through his innovative work on enzymatic synthesis. With a focus on enhancing the production of valuable compounds, Hoffmann stands out as a notable inventor in modern science.
Latest Patents
Hoffmann holds one patent that showcases his groundbreaking method for the production of baccatin-III by enzymatic synthesis. This innovative approach involves a continuous synthesis process utilizing enzymatic acetylations of 10-deacetyl baccatin-III (10-DAB) in an enzyme reactor. The patent details a method where an aqueous reaction batch containing a purified acetyl transferase from a Taxus species interacts with various components, including acetyl compounds and a protective colloid. Notably, the solution is separated from an organic solvent through a semipermeable membrane, facilitating the extraction of baccatin-III while maintaining the efficiency of the reaction.
Career Highlights
Hoffmann's career is marked by his role at the Institut für Bioanalytik, Umwelttoxikologie und Biotechnologie Halle GmbH, where he engages in advanced research and development in biotechnological processes. His expertise and innovative thinking have enabled him to contribute significantly to the field, particularly in the synthesis of compounds that play crucial roles in pharmaceuticals.
Collaborations
Throughout his career, Matthias Hoffmann has collaborated with esteemed colleagues, including Konrad Glund and Wolfram Weckwerth. These collaborations have enriched his research endeavors, fostering an environment of innovation and scientific exploration that enhances the understanding and application of enzymatic processes.
Conclusion
Matthias Hoffmann’s inventive work and his patented method for producing baccatin-III underscore the potential of enzymatic synthesis in advancing biotechnological applications. His contributions not only reflect his dedication as an inventor but also pave the way for future innovations in the synthesis of vital pharmaceutical compounds. As research continues, Hoffmann's method may lead to increased yields and enhanced methodologies in the production of critical medicinal substances.