Matthew Sleeman

Title: The Innovative Contributions of Matthew Sleeman in Pharmaceutical Research

Introduction

Matthew Sleeman is a notable inventor based in White Plains, NY, who has made significant contributions to the field of pharmaceutical research. With a total of three patents to his name, Sleeman's work primarily focuses on compounds and therapeutic applications that target the liver X receptor, which plays a crucial role in metabolism and immune response.

Latest Patents

Matthew Sleeman's latest patents include:

1. **Bis-octahydrophenanthrene carboxamide derivatives and protein conjugates thereof for use as LXR agonists:** This patent encompasses compounds designed to treat liver-related diseases by targeting the liver X receptor. It highlights the potential of bis-octahydrophenanthrene carboxamides and their antibody-drug conjugates to offer innovative treatment methods.

2. **Anti-GITR antibodies and uses thereof:** This patent details antibodies that specifically bind to the glucocorticoid-induced tumor necrosis factor receptor (GITR). It lays out compositions and treatment methods that utilize these antibodies, showcasing their therapeutic potential.

Career Highlights

Matthew Sleeman is currently associated with Regeneron Pharmaceuticals, Inc., a prominent biotechnology company engaged in the discovery and development of various medicines. His role in research and development has positioned him as a valuable asset in the ongoing quest for novel therapeutic solutions.

Collaborations

Throughout his career, Sleeman has collaborated with notable colleagues such as William C. Olson and Viktoria Gusarova. These partnerships have facilitated the advancement of innovative research initiatives and contributed to the successful development of therapeutic compounds.

Conclusion

Matthew Sleeman exemplifies the spirit of innovation and collaboration that drives progress in the pharmaceutical industry. With his patents paving the way for new treatment methods, he continues to influence the landscape of medical research and development, leaving a lasting impact on the field.