This inventor holds 3 USPTO granted patents. Top assignee: Genesis Research & Development Corporation Limited. Active years: 2001-2006.
Location History:
- Auckland, NZ (2001)
- Royston, GB (2004)
- GT Bradley, GB (2006)
Company Filing History:
Years Active: 2001-2006
Title: Innovations by Matthew Sleeman
Introduction
Matthew Sleeman is an accomplished inventor based in GT Bradley, GB. He has made significant contributions to the field of biomedical research, particularly in enhancing immune responses through innovative methods and polypeptides. With a total of 3 patents, his work has the potential to impact various medical conditions.
Latest Patents
Sleeman's latest patents include groundbreaking methods for enhancing immune responses by utilizing fibroblast growth factor receptor 5 (FGFR5) polypeptides. These patents provide isolated FGFR5 polypeptides and polynucleotides that encode such polypeptides. Additionally, they introduce modulators of FGFR5 gene expression and binding molecules that can specifically bind to and either agonize or antagonize FGFR5 polypeptide function. These specific binding molecules include antibodies and functional fragments, as well as scFv and Camelidae heavy chain IgG, which can modulate FGFR5 activity. This innovation is particularly relevant for treating diseases such as osteopontin-mediated autoimmune diseases, including systemic lupus erythematosus, bone disorders like osteoporosis and osteopetrosis, and various cancers, including cellular carcinomas such as hepatocellular carcinomas.
Career Highlights
Matthew Sleeman is currently associated with Genesis Research & Development Corporation Limited, where he continues to advance his research and innovations. His work is characterized by a strong focus on the intersection of immunology and therapeutic applications.
Collaborations
Sleeman has collaborated with notable colleagues, including Nevin Abernethy and Rene Onrust, to further enhance the impact of his research and innovations.
Conclusion
Matthew Sleeman's contributions to the field of biomedical research through his patents and collaborations highlight his role as a significant inventor. His work has the potential to lead to advancements in the treatment of various diseases, showcasing the importance of innovation in healthcare.