Matthew P Grealish

Title: Innovations by Matthew P Grealish

Introduction

Matthew P Grealish is an accomplished inventor based in San Diego, California. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel compounds with antineoplastic and antimicrobial properties. His work has led to the filing of two patents that showcase his innovative approach to drug synthesis and application.

Latest Patents

Matthew P Grealish's latest patents include "Structural modification of resveratrol: sodium resverastatin phosphate" and "Hydroxyphenstatin and the prodrugs thereof." The first patent describes novel compounds derived from structural modifications of resveratrol and combretastatin A-4, which exhibit antineoplastic and antimicrobial activity. The compounds include various forms of trimethoxystilbene and sodium resverastatin phosphate, which are intended for use in pharmaceutical compositions for treating cancer in mammals. The second patent focuses on hydroxyphenstatin, a potent inhibitor of tubulin polymerization, which has shown effective antineoplastic activity against human cancer cells and murine P388 lymphocytic leukemia cells.

Career Highlights

Throughout his career, Matthew has worked with notable institutions such as Arizona State University and the Arizona Board of Regents. His research has contributed to advancements in cancer treatment and the development of new pharmaceutical agents.

Collaborations

Matthew has collaborated with George R Pettit, a fellow researcher, to further explore the potential of his innovative compounds. Their joint efforts have enhanced the understanding of the mechanisms behind the antineoplastic properties of the compounds developed.

Conclusion

Matthew P Grealish is a notable inventor whose work in pharmaceutical innovation has the potential to impact cancer treatment significantly. His patents reflect a commitment to advancing medical science through innovative research and development.