Location History:
- San Francisco, CA (US) (2003)
- Berkeley, CA (US) (2001 - 2011)
Company Filing History:
Years Active: 2001-2011
Title: Innovations of Matthew J Hart
Introduction
Matthew J Hart is a notable inventor based in Berkeley, CA. He has made significant contributions to the field of biotechnology, particularly in the area of guanine exchange factors and their applications in therapeutics and diagnostics. With a total of four patents to his name, Hart's work has the potential to impact various medical and research fields.
Latest Patents
Hart's latest patents focus on nucleic acids and polypeptides related to a guanine exchange factor of Rho GTPase. His inventions describe the modulation of cell signaling pathways through the activity of a GTPase, specifically highlighting the p115 Rho-GEF. The patents detail isolated p115 Rho-GEF polypeptides, nucleic acids coding for these polypeptides, and their derivatives. Additionally, the inventions encompass methods for utilizing these polypeptides and nucleic acids in therapeutics, diagnostics, and as research tools. Another aspect of his work involves antibodies and ligands that recognize p115 Rho-GEF, as well as methods for treating conditions associated with Rho GTPase.
Career Highlights
Matthew J Hart is currently associated with Onyx Pharmaceuticals, Inc., where he continues to advance his research and innovations. His work at Onyx has allowed him to collaborate with other experts in the field, further enhancing the impact of his inventions.
Conclusion
Matthew J Hart's contributions to biotechnology through his patents on guanine exchange factors demonstrate his commitment to advancing medical science. His work has the potential to lead to significant advancements in therapeutics and diagnostics.