Matthew Charles

Title: Innovations by Inventor Matthew Charles

Introduction

Matthew Charles is an accomplished inventor based in St. Louis Park, MN (US). He has made significant contributions to the field of biotechnology, particularly in the development of human tissue kallikrein-1 glycosylation isoforms. With a total of 3 patents to his name, Charles continues to push the boundaries of innovation in his field.

Latest Patents

One of his latest patents focuses on "Human tissue kallikrein 1 glycosylation isoforms." This patent provides preparations of tissue kallikrein-1 (KLK1) glycoforms that have a defined number of oligosaccharide units per KLK1 molecule. It also includes mixtures of such glycoforms, pharmaceutical compositions containing these glycoforms, methods of obtaining the rhKLK1 glycoforms, and their therapeutic uses. Another significant patent is titled "Formulations of human tissue kallikrein-1 for parenteral delivery and related methods." This patent presents high concentration compositions of tissue kallikrein-1 (KLK1) and outlines methods for parenterally administering these compositions to improve systemic pharmacokinetics, bioavailability, safety, and convenience.

Career Highlights

Matthew Charles is currently associated with Diamedica Inc., where he applies his expertise in biotechnology to develop innovative solutions. His work has been instrumental in advancing the understanding and application of tissue kallikrein-1 in therapeutic settings.

Collaborations

Throughout his career, Charles has collaborated with notable colleagues, including Tadeusz Kolodka and Mark F Williams. These collaborations have further enriched his research and development efforts.

Conclusion

Matthew Charles exemplifies the spirit of innovation in biotechnology through his patents and contributions to the field. His work continues to pave the way for advancements in therapeutic applications of human tissue kallikrein-1.