Location History:
- Point Reyes Station, CA (US) (2006 - 2009)
- Fairfax, CA (US) (2008 - 2017)
- San Rafael, CA (US) (2012 - 2019)
Company Filing History:
Years Active: 2006-2019
Title: The Innovative Contributions of Matt Lyttle in the Field of Nucleic Acid Technology
Introduction
Matt Lyttle, an accomplished inventor based in San Rafael, California, has made significant strides in the field of nucleic acid technology. With a remarkable portfolio of 17 patents, Lyttle is known for his innovative approach to developing efficient quenchers and nucleic acid probes that enhance research and application in molecular biology.
Latest Patents
Among his latest advancements, Lyttle's invention of "Dark Quenchers for Donor-Acceptor Energy Transfer" introduces a family of quenchers termed Black Hole Quenchers (BHQs). These quenchers are proficient in depleting excited state energy while remaining largely non-fluorescent. The invention also encompasses methods for utilizing BHQs, various probes incorporating these quenchers, and techniques for implementing the probes in scientific applications.
In addition, Lyttle has developed "Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes," which provide a novel class of solid supports designed for synthesizing modified oligomers of nucleic acids. These probes feature components that stabilize the hybridization of nucleic acids and include moieties such as intercalators and conformational stabilizing elements. This invention promises to enhance the stability and efficacy of nucleic acid probing techniques.
Career Highlights
Lyttle's career has been marked by his role at Biosearch Technologies, Inc., where he has been instrumental in pushing the boundaries of nucleic acid research and development. His extensive experience and innovative mindset have positioned him as a valuable asset in the field.
Collaborations
Throughout his career, Lyttle has collaborated with notable professionals such as Ronald M. Cook and Daren Dick. These partnerships have played a crucial role in driving forward the research and application of his inventions, reinforcing the importance of teamwork in scientific advancement.
Conclusion
Matt Lyttle stands out as a pivotal figure in the realm of nucleic acid technology. His substantial contributions, particularly within the context of efficient energy transfer and stabilization of nucleic acids, underscore the impact of his work on scientific research and application. With a continued focus on innovation, Lyttle is poised to make even greater strides in his field.