Gockhausen, Switzerland

Mathias Schmelcher


Average Co-Inventor Count = 3.0

ph-index = 1


Company Filing History:


Years Active: 2015

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1 patent (USPTO):Explore Patents

Title: The Innovations of Mathias Schmelcher

Introduction

Mathias Schmelcher is an innovative inventor based in Gockhausen, Switzerland. He has made significant contributions to the field of antimicrobial research, particularly in addressing the challenges posed by antibiotic-resistant bacteria. His work is crucial in the fight against infections that are increasingly difficult to treat.

Latest Patents

Mathias Schmelcher holds one patent that focuses on combating methicillin-resistant Staphylococcus aureus (MRSA) and multi-drug resistant strains. These strains are becoming prevalent in both human and veterinary clinics, leading to high annual losses in the dairy industry due to bovine mastitis. His research highlights the potential of bacteriophage endolysins as a new source of antimicrobials. The endolysin of prophage φSH2 from strain JCSC1435 exhibits lytic activity against live staphylococcal cells. His findings indicate that the CHAP domain of the endolysin shows three-fold higher activity than the full-length protein, with enhanced activity in the presence of bivalent calcium ions.

Career Highlights

Mathias Schmelcher is associated with the United States of America, as represented by the Secretary of Agriculture. His work has been instrumental in developing new strategies to treat infections caused by antibiotic-resistant bacteria. His research has implications for both human health and veterinary medicine.

Collaborations

Some of his notable coworkers include David M Donovan and Igor V Abaev. Their collaborative efforts contribute to advancing the understanding and treatment of bacterial infections.

Conclusion

Mathias Schmelcher's innovative work in antimicrobial research is paving the way for new treatments against antibiotic-resistant infections. His contributions are vital for both the medical and agricultural sectors, highlighting the importance of continued research in this critical area.

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