Company Filing History:
Years Active: 1992
Title: Massoud Arvanaghi: Innovator in Tetrazolium Compounds
Introduction
Massoud Arvanaghi is a notable inventor based in Hackensack, NJ (US). He has made significant contributions to the field of chemistry, particularly in the development of tetrazolium halide compounds. His innovative work has implications in histological staining and immunological assays.
Latest Patents
Arvanaghi holds a patent for "Tetrazolium halide compounds and methods." The patent describes compounds of the formula DNB-TZ(P2)(P3), where TZ represents a tetrazolium ring, DNB is 5-(2,4-dinitrophenyl), X is a halide, and P2 and P3 are independently halophenyl, nitrophenyl, or phenyl. One of the key compounds, INDT 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-dinitrophenyl) tetrazolium bromide, exhibits facile reduction to insoluble chromophoric formazan, which is advantageous compared to the chromagen INT. The structural difference between INDT and INT lies in the substitution at the 5-position on the tetrazolium ring, where INDT has 2,4-dinitrophenyl instead of phenyl. These compounds, including INDT, are valuable as chromagens for histological staining and in enzyme-amplified staining as part of immunological or hybridization assays.
Career Highlights
Massoud Arvanaghi is associated with Fisher Scientific Company, where he continues to advance his research and development efforts. His work has garnered attention for its practical applications in scientific research and diagnostics.
Collaborations
Throughout his career, Arvanaghi has collaborated with esteemed colleagues, including David J Brigati and Sreeramulu Nagubandi. These collaborations have contributed to the successful development and application of his patented compounds.
Conclusion
Massoud Arvanaghi's contributions to the field of chemistry, particularly through his patent on tetrazolium halide compounds, highlight his innovative spirit and dedication to advancing scientific knowledge. His work continues to impact histological and immunological research, showcasing the importance of innovation in the scientific community.