Company Filing History:
Years Active: 1997
Title: Massimo Lombardo: Innovator in Hybridization Assays
Introduction
Massimo Lombardo is a notable inventor based in Framingham, MA (US). He has made significant contributions to the field of hybridization assays, particularly in improving their sensitivity. His innovative methods have the potential to enhance the accuracy and reliability of various biological assays.
Latest Patents
Lombardo holds a patent for "Methods for improving the sensitivity of hybridization assays." This patent discloses techniques that reduce non-specific binding (NSB) and non-specific hybridization (NSH). The methods include a washing technique utilizing tetraalkylammonium salts at high temperatures, as well as release methods that allow for the recapture of probe-target complexes from solid supports. The combination of these methods leads to a substantial reduction in NSB and NSH without the need for multiple rounds of release and recapture of target nucleic acids.
Career Highlights
Massimo Lombardo is associated with Amoco Corporation, where he has applied his expertise in the development of innovative solutions in the field of hybridization assays. His work has been instrumental in advancing the methodologies used in biological research and diagnostics.
Collaborations
Lombardo has collaborated with notable colleagues, including Mark L Collins and Cecile Blomquist. These partnerships have contributed to the successful development and implementation of his patented methods.
Conclusion
Massimo Lombardo's contributions to the field of hybridization assays exemplify the impact of innovative thinking in scientific research. His patented methods represent a significant advancement in improving assay sensitivity, which can lead to more accurate biological analyses.