Company Filing History:
2 out of 12 
1 out of 13 
1 out of 10 Years Active: 2002-2014
Title: Massimo Bresciani: Innovator in Pharmaceutical Activation Processes
Introduction
Massimo Bresciani is a notable inventor based in Trieste, Italy. He has made significant contributions to the field of pharmaceuticals, particularly in the activation of water-insoluble drugs. With a total of 4 patents to his name, Bresciani's work focuses on enhancing the solubility and bioavailability of various drugs.
Latest Patents
One of his latest patents is titled "Process of thermodynamical activation of water-insoluble drugs loaded into cross-linked polymers." This invention outlines a method for preparing a highly activated composite of water-insoluble drugs. The process involves co-grinding the drug with a cross-linked polymer and then exposing the mixture to water or water vapors. The resulting composite is characterized by a high amount of drug in an easily soluble amorphous form, reduced amounts in a nanocrystalline form, and is free from practically insoluble drug crystals.
Another significant patent is the "Process for activation of drugs in a vibrational mill." This process aims to increase the solubility and bioavailability of drugs through a specific method carried out in a vibrational mill. It emphasizes the importance of the proportions between the drug and pharmaceutical carrier, as well as the empty volume among the grinding means. This innovative approach results in pharmaceutical powders with a high and consistent degree of activation, regardless of the drug and carrier used.
Career Highlights
Bresciani has worked with prominent companies in the pharmaceutical industry, including Eurand Pharmaceuticals, Ltd. and Eurand International S.p.a. His experience in these organizations has contributed to his expertise in drug activation processes.
Collaborations
Throughout his career, Massimo Bresciani has collaborated with notable colleagues such as Luca Dobetti and Fabio Carli. These partnerships have likely enriched his research and development efforts in the pharmaceutical field.
Conclusion
Massimo Bresciani's innovative work in the activation of water-insoluble drugs has made a significant impact on the pharmaceutical industry. His patents reflect a commitment to improving drug solubility and bioavailability, which is crucial for effective medical treatments.
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