This inventor holds 1 USPTO granted patent and 2 published patent applications. Top assignee: Stellenbosch University. Active years: 2025.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2025
Title: Masilo Charles Manyelo: Innovator in Tuberculous Meningitis Diagnosis
Introduction
Masilo Charles Manyelo is a notable inventor based in Parow Valley, South Africa. He has made significant contributions to the field of medical diagnostics, particularly in the area of tuberculous meningitis (TBM). His innovative work has the potential to improve the accuracy and efficiency of diagnosing this serious condition.
Latest Patents
Masilo Charles Manyelo holds a patent for "Biomarkers for diagnosing tuberculous meningitis." This patent includes methods, devices, kits, and computer-implemented methods for diagnosing and optionally treating TBM. One embodiment of the method involves testing a cerebrospinal fluid (CSF) sample from a subject suspected of having TBM for the presence of myeloperoxidase (MPO) and at least two other biomarkers. These biomarkers may include interferon-gamma (IFN-γ), soluble intercellular adhesion molecule-1 (sICAM-1), vascular endothelial growth factor A (VEGF-A), and chemokine (C-X-C motif) ligand 8 (CXCL8). Additionally, the method can also involve testing a blood sample for biomarkers such as adipsin (complement factor D), Ab42, and interleukin-10 (IL-10).
Career Highlights
Masilo Charles Manyelo is affiliated with Stellenbosch University, where he continues to advance his research and innovation in medical diagnostics. His work is crucial in addressing the challenges associated with diagnosing TBM, a condition that can have severe consequences if not identified and treated promptly.
Collaborations
Masilo collaborates with esteemed colleagues, including Gerhard Walzl and Novel Njweipi Chegou. Their combined expertise enhances the research and development of effective diagnostic methods for TBM.
Conclusion
Masilo Charles Manyelo's contributions to the field of medical diagnostics, particularly through his patent on biomarkers for diagnosing tuberculous meningitis, highlight his role as an innovator. His work not only advances scientific knowledge but also has the potential to save lives through improved diagnostic techniques.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile