Masayuki Shibasaki

Title: Innovations of Masayuki Shibasaki

Introduction

Masayuki Shibasaki is a notable inventor based in Tokyo, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in developing remedies for overactive bladder conditions. With a total of three patents to his name, Shibasaki's work has garnered attention in the medical community.

Latest Patents

Shibasaki's latest patents focus on a remedy for overactive bladder, which comprises an acetic acid anilide derivative as the active ingredient. The compound, specifically (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt, has demonstrated a potent bladder relaxation effect in isolated rat bladder smooth muscle relaxation tests. It dose-dependently lowers the contraction frequency of rhythmic bladder contractions in rat rhythmic bladder contraction measurement tests. Furthermore, it prolongs the urination intervals in urination functions measurement tests on cyclophosphamide-induced overactive bladder model rats. Owing to these effects, the compound is considered useful as a remedy for overactive bladder.

Career Highlights

Throughout his career, Masayuki Shibasaki has worked with prominent companies in the pharmaceutical industry. Notable among these are Astellas Pharma GmbH and Yamanouchi Pharmaceutical Company Ltd. His work in these organizations has contributed to advancements in medical treatments and therapies.

Collaborations

Shibasaki has collaborated with esteemed colleagues, including Toshiyuki Takasu and Shuichi Sato. These partnerships have played a crucial role in the development of his innovative solutions.

Conclusion

Masayuki Shibasaki's contributions to the field of pharmaceuticals, particularly in developing remedies for overactive bladder, highlight his innovative spirit and dedication to improving medical treatments. His patents and collaborations reflect a commitment to advancing healthcare solutions.