Location History:
- Tsukuba, JP (2010 - 2014)
- Chuo-ku, JP (2014)
Company Filing History:
Years Active: 2010-2014
Title: Inventor Masashi Ukai – A Pioneer in Overactive Bladder Remedies
Introduction
Masashi Ukai is a notable inventor based in Tsukuba, Japan, known for his significant contributions to pharmaceuticals, particularly in the treatment of overactive bladder conditions. With a remarkable portfolio of four patents, Ukai is dedicated to advancing medical science through innovative solutions.
Latest Patents
One of his latest inventions is a remedy for overactive bladder which comprises an acetic acid anilide derivative as the active ingredient, specifically (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt. This compound demonstrates a potent bladder relaxation effect, as evidenced by various tests. In isolated rat bladder smooth muscle relaxation tests, it dose-dependently reduces contraction frequency and prolongs urination intervals in cyclophosphamide-induced overactive bladder model rats. The findings position this compound as a viable remedy for managing overactive bladder symptoms.
Another important patent of Ukai is a pharmaceutical composition aimed at treating overactive bladder. This formulation incorporates (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}acetanilide and (3R)-quinuclidin-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate, both as active ingredients. This composition specifically targets various symptoms associated with overactive bladder, such as urinary urgency, pollakiuria, and urinary incontinence.
Career Highlights
Masashi Ukai has established his career at Astellas Pharma GmbH, a prestigious pharmaceutical company known for its commitment to developing innovative medical solutions. His work is instrumental in shaping new therapeutic approaches in treating urinary disorders.
Collaborations
Throughout his career, Ukai has collaborated with notable colleagues, including Toshiyuki Takasu and Shuichi Sato. These partnerships have facilitated the exchange of ideas and has led to advancements in the field of pharmacology, particularly in remedies for bladder-related ailments.
Conclusion
Masashi Ukai's innovative approach and significant contributions to the field of pharmaceuticals underscore his role as a prominent inventor. His latest patents are poised to make a substantial impact on the treatment of overactive bladder conditions, enhancing the quality of life for many individuals affected by this disorder.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.