Weston, Canada

Masanaru Misawa


Average Co-Inventor Count = 3.4

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 1989-1990

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2 patents (USPTO):Explore Patents

Title: The Innovative Journey of Masanaru Misawa

Introduction

Masanaru Misawa is a notable inventor based in Weston, CA. His work primarily focuses on the field of biopharmaceuticals, contributing significantly to the development of alkaloids that play crucial roles in cancer treatment.

Latest Patents

Masanaru Misawa holds two patents that showcase his innovative contributions to the field:

1. **Enzymatic Preparation of 3',4'-anhydrovinblastine** - This invention pertains to the enzymatic coupling of catharanthine and vindoline, utilizing an iron-containing compound such as peroxidase, optionally in the presence of a peroxide. This innovative method results in substantially enhanced yields of 3',4'-anhydrovinblastine, a precursor of the anti-tumor alkaloids vincristine and vinblastine.

2. **Extraction of Alkaloids of Catharanthus roseus Tissue** - This patent details a process for selectively concentrating alkaloids found in Catharanthus roseus tissue. It involves aqueous extraction of ground tissue followed by extraction with an organic solvent, specifically ethyl acetate. The method enhances the yield of catharanthine, vindoline, and 3',4'-anhydrovinblastine by incorporating additives such as acid, salt, or hydrogen peroxide into the aqueous extraction medium, and further enhancement is achieved through sodium borohydride.

Career Highlights

Masanaru Misawa has made significant strides in his career, particularly during his time at Allelix, Inc. and Allelix Biopharmaceuticals Inc. His inventions have laid the groundwork for advancements in treating cancer, demonstrating his commitment to innovation in biopharmaceutical research.

Collaborations

Throughout his career, Misawa has collaborated with esteemed colleagues such as Anne E. Goodbody and Colin D. Watson. These partnerships have fostered a creative environment that nurtures groundbreaking research and innovation in the field.

Conclusion

Masanaru Misawa’s contributions to the field of biopharmaceuticals through his patents and collaborations highlight the importance of innovation in the quest to combat cancer. His work continues to serve as an inspiration for future inventors and researchers committed to making a difference in medical science.

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