Masahiro Ogura

Title: Masahiro Ogura: Innovator in Optically Active Amino Compounds

Introduction

Masahiro Ogura, an accomplished inventor based in Ono, Japan, has made significant strides in the field of organic chemistry through his innovative methods for producing optically active amino compounds. With a total of 10 patents to his name, Ogura’s inventions exemplify the potential for microbial enzymes to create efficient and cost-effective solutions in the synthesis of valuable chemical compounds.

Latest Patents

Ogura’s latest patents focus on the development of methods to prepare optically active compounds that predominantly contain (R)-amino compounds. One of his notable inventions includes a technique utilizing microbial enzymes to achieve this synthesis efficiently and inexpensively. This process is characterized by the stereoselective transamination of a ketone compound using an amino donor, primarily a primary amine. Essential to this method is a polypeptide with stereoselective transaminase activity, which can be derived from a culture of microorganisms belonging to the genus Arthrobacter.

His advancements not only simplify the preparation of optically active (R)-amino compounds but also enhance the yield of these compounds, which are crucial in pharmaceuticals and fine chemicals. This innovative approach addresses challenges that have historically limited the accessibility of these compounds.

Career Highlights

Throughout his career, Ogura has worked for notable companies, including Kanegafuchi Kagaku Kogyo Kabushiki Kaisha and Kaneka Corporation. His extensive experience in these organizations has contributed to his in-depth understanding of organic synthesis and the application of microbial biotechnology in the chemical industry.

Collaborations

During his innovative journey, Ogura has collaborated with esteemed colleagues, including Junzo Hasegawa and Kiyoshi Watanabe. These collaborations have facilitated knowledge exchange and have played a crucial role in enhancing the practical applications of his research in the field of organic chemistry.

Conclusion

Masahiro Ogura’s contributions to the domain of optically active amino compound synthesis reflect his commitment to innovation and advancement in organic chemistry. With a portfolio of patents that highlight his expertise and creativity, Ogura is paving the way for new methodologies that will undoubtedly influence the future of chemical synthesis and applications in various industries.