Masaharu Mukoyama

Title: Masaharu Mukoyama: Innovator in Genetic Engineering

Introduction

Masaharu Mukoyama is a prominent inventor based in Tsukuba, Japan. He has made significant contributions to the field of genetic engineering, particularly in the modification of gram-positive bacteria. His innovative approaches have led to advancements in biotechnology and fermentation processes.

Latest Patents

Mukoyama holds 2 patents that showcase his expertise. His latest patents include a method for converting the genome sequence of gram-positive bacteria by specifically converting nucleic acid bases of targeted DNA sequences. This invention provides a method of modifying a targeted site of gram-positive bacteria with double-stranded DNA. The method involves contacting the double-stranded DNA with a complex that includes a nucleic acid sequence-recognizing module and a nucleic acid base converting enzyme. This allows for the conversion, deletion, or insertion of nucleotides in the targeted site without cleaving at least one strand of the double-stranded DNA. Additionally, he has developed a method for producing butanol using genetically modified microorganisms, enhancing the efficiency of butanol fermentation.

Career Highlights

Throughout his career, Mukoyama has worked with notable organizations, including Nippon Shokubai Co., Ltd. and Kobe University. His work has been instrumental in advancing the understanding and application of genetic modifications in microorganisms.

Collaborations

Mukoyama has collaborated with esteemed colleagues such as Eita Ichige and Keiji Nishida. These partnerships have further enriched his research and contributions to the field.

Conclusion

Masaharu Mukoyama's innovative work in genetic engineering has paved the way for advancements in biotechnology. His patents reflect his commitment to enhancing fermentation processes and modifying genetic sequences, making a lasting impact in his field.